16588-16-2

Basic information

• Product Name: ETHYL 4-CHLORO-3-NITROBENZOATE
• Synonyms: RARECHEM AL BI 0170;ETHYL 4-CHLORO-3-NITROBENZOATE;4-CHLORO-3-NITROBENZOIC ACID ETHYL ESTER;Ethyl 4-chloro-3-nitrobenzoate,98%;4-CHLORO-3-NITROBENZOATE
• CAS NO: 16588-16-2
• Molecular Formula: C₉H₈ClNO₄
• Molecular Weight: 229.62
• Product Categories: Aromatic Esters
• Mol File: 16588-16-2.mol
• Article Data: 22

Chemical Properties

• Melting Point: 57-61 °C
• Boiling Point: 326.22 °C at 760 mmHg
• Flash Point: 151.093 °C
• Appearance: pale yellow crystalline powder
• Density: 1.37 g/cm³
• Vapor Pressure: 0.000219mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ETHYL 4-CHLORO-3-NITROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-CHLORO-3-NITROBENZOATE(16588-16-2)
• EPA Substance Registry System: ETHYL 4-CHLORO-3-NITROBENZOATE(16588-16-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• Hazardous Substances Data: 16588-16-2(Hazardous Substances Data)

Usage

Chemical Properties

pale yellow crystalline powder

InChI:InChI=1/C9H8ClNO4/c1-2-15-9(12)6-3-4-7(10)8(5-6)11(13)14/h3-5H,2H2,1H3

Upstream product

• 64-17-5 ethanol 
• 38818-50-7 4-chloro-3-nitro-benzoyl chloride 
• 75-03-6 ethyl iodide 
• 96-99-1 4-chloro-3-nitrobenzoate 
• 14719-83-6 methyl 3-nitro-4-chlorobenzoate 

Downstream Products

• 55912-20-4 4-chloro-3-nitrobenzyl alcohol 
• 367-80-6 ethyl 4-fluoro-3-nitrobenzoate 
• 22057-46-1 ethyl 4-benzylthio-3-nitrobenzoate 
• 629643-57-8 3-nitro-4-(2-oxo-cyclopentyl)-benzoic acid ethyl ester 
• 637041-66-8 ethyl 4-(tert-butylamino)-3-nitrobenzoate 
• 622848-24-2 3-nitro-4-p-toluidino-benzoic acid ethyl ester 
• 19013-10-6 ethyl 4-hydroxy-3-nitrobenzoate 
• 302836-52-8 C₁₁H₁₁NO₆S 
• 310451-70-8 C₁₆H₂₃N₃O₅ 
• 691847-97-9 4-mercapto-3-nitro benzoic acid ethyl ester 
• 773137-21-6 ethyl 4-(4-chlorophenylthio)-3-nitrobenzoate 
• 260788-72-5 ethyl 4-(4-methoxyphenoxy)-3-nitrobenzoate 
• 110073-83-1 2-phenyl-indole-6-carboxylic acid 

Relevant articles and documents

Novel [1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivatives embedded with benzimidazole moiety as potent antioxidants

Fourteen novel [1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivatives bearing benzimidazole moiety (7a-n) have been synthesized using the one-pot nitro reductive cyclization method. All the synthesized compounds were confirmed by 1H nuclear magne

Benzo[d]imidazol-5-yl)-5-(substituted)-1,3,4-Oxadiazoles: Synthesis, anticancer, antimicrobial and in silico studies

Background: Cancer is a fatal disease for mankind; continuous research is still going on for the invention of potent anticancer drugs. In this view, 1, 3, 4-Oxadiazoles are privileged molecules which attracted medicinal chemists towards their anticancer p

The Suzuki–Miyaura Cross-Coupling as the Key Step in the Synthesis of 2-Aminobiphenyls and 2,2'-Diaminobiphenyls: Application in the Synthesis of Schiff Base Complexes of Zn

2-Nitrophenylboronic acids serve as interesting starting materials for the construction of biphenyl- and terphenyl-based amines if subjected to the Suzuki–Miyaura reaction. Unfortunately, these boronic acids suffer from low reactivity in Suzuki reactions, alongside their low stability in the presence of Pd. Herein, a general method for the construction of 2-nitro-substituted bi- and terphenyls is presented, with special emphasis on the synthesis of 2-amino-2'-nitrobi- and terphenyls. Comparisons are made with other boronic acids that have some of the aforementioned issues. Finally, the application of the obtained 2-amino-2'-nitrobi- and terphenyls as starting materials for the synthesis of bi- and terphenyl based di- and triamines is encountered for, with emphasis on the use of these amines as precursors for Schiff base ligands. In addition, the synthesis of some Zn complexes of these ligands is presented.