872-79-7Relevant academic research and scientific papers
Monocyclic, substituted imidazoles as glycosidase inhibitors
Magdolen, Peter,Vasella, Andrea
, p. 2454 - 2469 (2007/10/03)
A range of 4-monosubstituted and 2,4-disubstituted 1H-imidazoles and 1H-imidazole-1-ethanols (R-C(4): CH2CH2Ph, CHOHCH 2Ph, Ph, or Me; R-C(2): CH2OH, CHOHCH2OH, CN, or CH2NHAc) were prepare
SYNTHESIS OF A CIMETIDINE ANALOGUE
Heiszman, Jozsef,Harsanyi, Kalman,Toke, Laszlo
, p. 2487 - 2491 (2007/10/02)
2-Hydroxymethyl-4-methylimidazole (2a) and 2,5-bis(hydroxymethyl)-4-methylimidazole (3a) have been synthesized and characterized.No reaction on the hydroxymethyl moieties in position 2 of these compounds could be observed with cysteamine under usual reaction conditions.The hydroxymethyl group in position 5 of compound 3a does react with cysteamine to give an intermediate leading to 3b and to cimetidine analogue 3c.
