872008-58-7Relevant academic research and scientific papers
Methods for producing D-beta-hydroxyamino acids
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Page/Page column 12, (2008/06/13)
An objective of the present invention is to provide efficient methods for producing D-β-hydroxyamino acids (formula 2 or 4), such as D-erythro-2-amino-3-cyclohexyl-3-hydroxypropionic acid, which are useful as intermediates in the synthesis of pharmaceutical products and others. The present invention makes it possible to efficiently produce D-erythro-2-amino-3-cyclohexyl-3-hydroxypropionic acid by cleaving unnecessary L-erythro-2-amino-3-cyclohexyl-3-hydroxypropionic acid in industrially feasible concentrations of DL-erythro-2-amino-3-cyclohexyl-3-hydroxypropionic acid used as starting material by using Pseudomonas putida-derived L-phenylserine aldolase.
