87221-47-4Relevant academic research and scientific papers
Mild and Efficient Preparation of γ-Substututed α,β-Unsaturated γ-Butyrolactones from Epoxides
Hanessian, Stephen,Hodges, Paul J.,Murray, Peter J.,Sahoo, Soumya P.
, p. 754 - 755 (2007/10/02)
Reaction of the dilithio derivative of phenylselenoacetic acid with epoxides leads to γ-substituted-α-phenylseleno-γ-butyrolactones, which upon oxidation-elimination, afford γ-substituted α,β-unsaturated γ-butyrolactones in high overall yield.
Preparation of 5-(2-Benzoyloxymethyl-4-methoxy)phenyl-2(5H)-furanone
Bhat, K. S.,Rao, A. S.
, p. 360 - 364 (2007/10/02)
5-Phenyl-2(5H)-furanone (11), 5-(2-methyl-4-methoxy)phenyl-2(5H)-furanone (16) and 5-(2-benzoyloxymethyl-4-methoxy)phenyl-2(5H)-furanone (6) have been prepared from γ-phenyl-γ-butyrolactone (9), γ-(2-methyl-4-methoxy)phenyl-γ-butyrolactone (14) and γ-(2-benzoyloxymethyl-4-methoxy)phenyl-γ-butyrolactone (4) respectively employing the method of Sharpless. 11 has been converted into 4-oxo-4-phenylbutanoic acid (7) on treatment with alkali.During the Wolff-Kishner reduction of 4-oxo-4-(2-methyl-2-methoxyphenyl)butanoic acid (12) the demethylated product 4-(2-methyl-4-hydroxy)phenylbutanoic acid (19) has also been obtained.
