87223-36-7Relevant academic research and scientific papers
CRTH2 MODULATORS
-
Page/Page column 71, (2011/06/28)
Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed. The compounds fall within a genus described by formula I:
INTRAMOLECULAR SULFONAMIDE-CARBOXAMIDE REARRANGEMENT.
Hovius, Klaas,Wagenaar, Anno,Engberts, Jan B. F. N.
, p. 3137 - 3140 (2007/10/02)
Several o-carboxy-N,N-dialkylbenzenesulfonamides rearrange intramolecularly to o-chlorosulfonyl-N,N-dialkylbenzamides upon treatment with an excess of thionyl chloride in an apolar solvent.
