26638-43-7Relevant articles and documents
Sulfonium ion-promoted traceless Schmidt reaction of alkyl azides
Ardiansah, Bayu,Kakiuchi, Kiyomi,Morimoto, Tsumoru,Tanimoto, Hiroki,Tomohiro, Takenori
supporting information, p. 8738 - 8741 (2021/09/08)
Schmidt reaction by sulfonium ions is described. General primary, secondary, and tertiary alkyl azides were converted to the corresponding carbonyl or imine compounds without any trace of the activators. This bond scission reaction through 1,2-migration of C-H and C-C bonds was accessible to the one-pot substitution reaction.
Method of preparing 2-chlorosulfonylmethyl benzoate from phthalic anhydride and urea
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, (2017/01/17)
The invention provides a method of preparing 2-chlorosulfonylmethyl benzoate from phthalic anhydride and urea. The method includes the steps of 1) adding solid phthalic anhydride and urea into a reaction kettle and heating the materials to 135-143 DEG C to carry out a reaction to prepare o-aminobenzene dicarboximide, feeding the o-aminobenzene dicarboximide with water and sodium hydroxide into a first tubular reactor, forcedly cooling the mixture to -12 - -15 DEG C; 2) adding methanol and a sodium hypochlorite solution to perform Hoffman degradation reaction, and separating the reaction product to obtain o-aminomethyl benzoate; 3) according to the same mass ratio, feeding the o-aminomethyl benzoate and a sodium nitrite solution to a second tubular reactor, cooling the reactants to 0 DEG C, and adding sulfuric acid to perform a diazo-reaction for 11.5-11.8 s; and 4) continuously performing a cyclic sulfurization oxidation tubular reaction for 2 h, when the reactants show a dark green color on an benzidine-ethylamine test paper, adding methylbenzene and separating the reactant to obtain the 2-chlorosulfonylmethyl benzoate. The method is safe and simple, is advanced and integrated, is high in synthesis efficiency, has less side reactions and greatly reduces influence due to human factors.
Method for continuously preparing 2-(chlorosulfonyl) methyl benzoate and device adopted for method
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Paragraph 0041; 0042, (2016/12/22)
The invention discloses a method for continuously preparing 2-(chlorosulfonyl) methyl benzoate and a device adopted for the method. The special device comprises a first mixer, a first tubular reactor, a second mixer, a second tubular reactor, a receiving tank, a fourth storage tank and a fifth storage tank. The first mixer, the first tubular reactor, the second mixer, the second tubular reactor and the receiving tank are sequentially connected. The fourth storage tank is connected with the second mixer sequentially through a fourth metering pump and a fourth flow meter. The fifth storage tank is connected with the second mixer sequentially through a fifth metering pump and a fifth flow meter. The first mixer is connected with a first storage tank, a second storage tank and a third storage tank. A first metering pump and a first flow meter are sequentially connected between the first storage tank and the first mixer. A second metering pump and a second flow meter are sequentially connected between the second storage tank and the first mixer. A third metering pump and a third flow meter are sequentially connected between the third storage tank and the first mixer. A backpressure valve is arranged between the second tubular reactor and an inlet of the receiving tank. The method and the device are environmentally friendly, safe and suitable for industrial production.
