872298-30-1Relevant academic research and scientific papers
Candida antarctica lipase B (CAL-B)-catalyzed carbon-sulfur bond addition and controllable selectivity in organic media
Lou, Feng-Wen,Liu, Bo-Kai,Wu, Qi,Lv, De-Shui,Lin, Xian-Fu
supporting information; experimental part, p. 1959 - 1962 (2009/08/07)
A novel enzymatic, promiscuous protocol for Candida antarctica lipase B (CAL-B)-catalyzed carbon-sulfur bond addition is described. Some control experiments have been designed to demonstrate the catalytic specificity of CAL-B. Selectivity between anti-Markovnikov addition and Markovnikov addition was achieved in different organic media. A series of thioether-containing ester functional groups was synthesized under the catalysis of CAL-B at 50°C. All the products were characterized by spectroscopic methods (IR, NMR, ESIMS).
