87231-36-5

Basic information

• Product Name: [(2S,3R)-1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-yl]-acetonitrile
• CAS NO: 87231-36-5
• Molecular Weight: 286.331
• Mol File: 87231-36-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(2S,3R)-1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-yl]-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [(2S,3R)-1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-yl]-acetonitrile(87231-36-5)
• EPA Substance Registry System: [(2S,3R)-1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-yl]-acetonitrile(87231-36-5)

Safety Data

• Hazardous Substances Data: 87231-36-5(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 90210-85-8 (2R,3S)-1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 90210-85-8 1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 83304-65-8 diethyl 1-benzyl-3-hydroxy-3-methyl-5-oxo-pyrrolidine-2,2-dicarboxylate 
• 87231-39-8 Methanesulfonic acid (2R,3R)-1-benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-ylmethyl ester 
• 83304-66-9 diethyl 3-acetyl-1-benzyl-4-oxo-2,2-azetidine-dicarboxylate 
• 87231-40-1 (3R,4R)-1-Benzyl-4-hydroxymethyl-3-(2-methyl-[1,3]dioxolan-2-yl)-azetidin-2-one 
• 56599-00-9 diethyl N-benzyl-2-aminomalonate 
• 143-33-9 sodium cyanide 
• 87231-37-6 (3R,4R)-1-Benzyl-4-iodomethyl-3-(2-methyl-[1,3]dioxolan-2-yl)-azetidin-2-one 
• 90210-84-7 1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidine-2,2-dicarboxylic acid diethyl ester 

Downstream Products

• 90210-81-4 1-benzyl-4-cyanomethyl-3-(1'-hydroxyethyl)azetidin-2-one 
• 77120-93-5 (2RS,3RS,4SR)-4-benzylamino-2-methyl-6-oxotetrahydropyran-3-carboxylic-acid hydrochloride 
• 108908-43-6 ((2S,3R)-3-Acetyl-1-benzyl-4-oxo-azetidin-2-yl)-acetonitrile 

Relevant articles and documents

SIMPLE AND CONDENSED β-LACTAMS-I. THE APPLICATION OF DIKETENE IN β-LACTAM SYNTHESIS. THE SYNTHESIS AND FUNCTIONAL GROUP MANIPULATIONS OF DIETHYL 3-ACETYL-4-OXOAZETIDINE-2,2-DICARBOXYLATES

Acetylation of the N-substituted diethyl aminomalonates 3a-3d with diketene furnished the ring tautomers 6a-6d of the expected acetoacetyl derivatives 5.By treatment with iodine and sodium ethoxide compounds 6a-6d are smoothly converted into the β-lactam