90210-81-4

Basic information

• Product Name: 1-benzyl-4-cyanomethyl-3-(1'-hydroxyethyl)azetidin-2-one
• CAS NO: 90210-81-4
• Molecular Weight: 244.293
• Mol File: 90210-81-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-4-cyanomethyl-3-(1'-hydroxyethyl)azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4-cyanomethyl-3-(1'-hydroxyethyl)azetidin-2-one(90210-81-4)
• EPA Substance Registry System: 1-benzyl-4-cyanomethyl-3-(1'-hydroxyethyl)azetidin-2-one(90210-81-4)

Safety Data

• Hazardous Substances Data: 90210-81-4(Hazardous Substances Data)

Upstream product

• 87231-36-5 [(2S,3R)-1-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-yl]-acetonitrile 
• 108908-43-6 ((2S,3R)-3-Acetyl-1-benzyl-4-oxo-azetidin-2-yl)-acetonitrile 

Downstream Products

• 77120-93-5 (2RS,3RS,4SR)-4-benzylamino-2-methyl-6-oxotetrahydropyran-3-carboxylic-acid hydrochloride 

Relevant articles and documents

Simple and Condensed β-Lactams. Part 7. Side Chain Extension of Some Azetidin-2-one Derivatives, and the Formation of Melillo's Lactone, a Strategic Intermediate in the Total Synthesis of Thienamycin, from 3-Acetyl-1-benzyl-4-cyanomethylazetidin-2-one

The oxoazetidinecarboxylic acids (2a) and (2b) and the homologous acid (8b) were converted by treatment of their chlorides with ethyl diazoacetate into the diazo esters (4a, b), and (1Ob), respectively.Irradiation of the diazo ester (4b) afforded the diet