872350-18-0Relevant articles and documents
Synthesis of oligodeoxyribonucleotides containing hydroxymethylphosphonate bonds in the phosphoramidite method and their hybridization properties
Ohkubo, Akihiro,Aoki, Katsufumi,Ezawa, Yusuke,Sato, Yuichi,Taguchi, Haruhiko,Seio, Kohji,Sekine, Mitsuo
, p. 8953 - 8957 (2007/10/03)
A set of diastereomeric TpT phosphoramidite building blocks, 1-f and 1-s, containing an alkaline-labile hydroxymethylphosphonate (HMP) linkage were synthesized. Dodecadeoxynucleotides incorporating the HMP bond were also synthesized by use of each stereoc