872355-64-1

Basic information

• Product Name: 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLIC ACID
• Synonyms: 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLIC ACID;4-AZAINDOLE-5-CARBOXYLIC ACID;4-Azaindole-5-carboxylic ...
• CAS NO: 872355-64-1
• Molecular Formula: C₈H₆N₂O₂
• Molecular Weight: 162.147
• Mol File: 872355-64-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 446.8°C at 760 mmHg
• Flash Point: 224°C
• Appearance: /
• Density: 1.506g/cm³
• Vapor Pressure: 9.1E-09mmHg at 25°C
• Refractive Index: 1.743
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLIC ACID(872355-64-1)
• EPA Substance Registry System: 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLIC ACID(872355-64-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 872355-64-1(Hazardous Substances Data)

Usage

Uses

1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid is used as a reactant for the preparation process of piperazinones as inhibitors of arenavirus replication.

InChI:InChI=1/C8H6N2O2/c11-8(12)7-2-1-5-6(10-7)3-4-9-5/h1-4,9H,(H,11,12)

Upstream product

• 67515-76-8 methyl 5-amino-2-pyridinecarboxylate 
• 55338-73-3 5-amino-2-cyanopyridine 
• 872355-62-9 5-acetylamino-5-trimethylsilanylethynyl-2-nicotinic acid methyl ester 
• 872355-61-8 5-amino-6-trimethylsilylacetylene-2-nicotinic acid methyl ester 
• 872355-60-7 methyl 5-amino-6-iodopyridine-2-carboxylate 
• 24242-20-4 5-amino-pyridine-2-carboxylic acid 
• 872355-63-0 methyl 1H-pyrrolo[3,2-b]pyridine-5-carboxylate 

Downstream Products

• 1401348-59-1 5-(3-(5-methoxypyridin-3-yl)-1-tosyl-1H-pyrrolo[3,2-b]pyridin-5-yl)-1,3,4-oxadiazol-2-amine 
• 1401348-58-0 methyl 3-(5-methoxypyridin-3-yl)-1-tosyl-1H-pyrrolo[3,2-b]pyridine-5-carboxylate 
• 1401348-57-9 C₁₅H₁₃IN₄O₃S 
• 1401348-56-8 5-(3-iodo-1-tosyl-1H-pyrrolo[3,2-b]pyridin-5-yl)-1,3,4-oxadiazol-2-amine 
• 1401348-55-7 methyl 3-iodo-1-tosyl-1H-pyrrolo[3,2-b]pyridine-5-carboxylate 
• 1401348-54-6 3-iodo-1-tosyl-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid 
• 1190311-30-8 3-iodo-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid 
• 1401345-13-8 5-(3-(2-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin-5-yl)-1,3,4-oxadiazol-2-amine 

Relevant articles and documents

AZAINDOLE DERIVATIVES AS INHIBITORS OF P38 KINASE

The invention is directed to methods to inhibit p38 kinase, preferably p38-α using compounds which are azaindoles wherein the azaindoles are coupled through an azacyclic linker to another cyclic moiety.