872356-75-7Relevant articles and documents
Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH
Ndonye, Rachel M.,Izmirian, Douglas P.,Dunn, Matthew F.,Yu, Karl O. A.,Porcelli, Steven A.,Khurana, Archana,Kronenberg, Mitchell,Richardson, Stewart K.,Howell, Amy R.
, p. 10260 - 10270 (2007/10/03)
The phytosphingosine-containing α-galactosylceramides (α-GalCers), KRN7000 and OCH, have been shown to activate NKT cells via interaction with CD1d, a member of the CD1 family of antigen presenting proteins. Evidence from KRN7000 stimulation of NKT cells