872356-79-1Relevant academic research and scientific papers
RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: Their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines
Tashiro, Takuya,Hongo, Naomi,Nakagawa, Ryusuke,Seino, Ken-ichiro,Watarai, Hiroshi,Ishii, Yasuyuki,Taniguchi, Masaru,Mori, Kenji
, p. 8896 - 8906 (2008/12/23)
RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 (1) with a sulfonamide linkage instead of an amide bond, were synthesized to examine their bioactivity for mouse natural killer (NK) T cells. RCAI-17, 22, 24-26, 29, 31, 34-36, and 8
Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH
Ndonye, Rachel M.,Izmirian, Douglas P.,Dunn, Matthew F.,Yu, Karl O. A.,Porcelli, Steven A.,Khurana, Archana,Kronenberg, Mitchell,Richardson, Stewart K.,Howell, Amy R.
, p. 10260 - 10270 (2007/10/03)
The phytosphingosine-containing α-galactosylceramides (α-GalCers), KRN7000 and OCH, have been shown to activate NKT cells via interaction with CD1d, a member of the CD1 family of antigen presenting proteins. Evidence from KRN7000 stimulation of NKT cells
