872357-77-2

Upstream product

• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 872357-89-6 (R)-N,N-dibenzyl-1-phenyl-1-heptyn-3-amine 
• 872357-91-0 ethyl 4-[3-(dibenzylamino)-1-heptynyl]benzoate 
• 872357-84-1 (R)-N,N-dibenzylhept-1-yn-3-amine 

Relevant academic research and scientific papers

Synthesis of enantiomerically enriched propargylamines by copper-catalyzed addition of alkynes to enamines

The first copper(I) bromide/Quinap-catalyzed synthesis of enantiomerically enriched propargylamines by addition of alkynes to enamines is reported. Various functionalized terminal alkynes add smoothly to N-protected enamines to afford the corresponding am

Enantioselective synthesis of propargylamines by copper-catalyzed addition of alkynes to enamines

Enantiomerically enriched, functionalized, and protected propargylamines are obtained under mild conditions in a new copper(I)/Quinap-catalyzed addition reaction of alkynes to enamines (see scheme).