872369-25-0

Upstream product

• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 872369-19-2 (3S,4S)-3-(tert-butyldimethylsilyloxy)-4-methyloctan-1-ol 
• 1584664-36-7 (2R,3S)-1-((S)-4-benzyl-2-thioxothiazolidin-3-yl)-5-(benzyloxy)-3-(tert-butyldimethylsilyloxy)-2-methylpentan-1-one 
• 1464823-37-7 (2R,3S)-1-((S)-4-benzyl-2-thioxothiazolidin-3-yl)-5-(benzyloxy)-3-hydroxy-2-methylpentan-1-one 
• 619-73-8 4-nitrobenzyl chloride 
• 872369-20-5 C₁₅H₃₂O₃Si 
• 872369-18-1 ((3S,4S)-1-(benzyloxy)-4-methyloct-5-en-3-yloxy)(tert-butyldimethylsilane) 
• 872369-16-9 (?)-(2S,3S)-5-(benzyloxy)-3-(tert-butyldimethylsilyloxy)-2-methylpentan-1-ol 
• 872369-17-0 (2R,3S)-5-(benzyloxy)-3-(tert-butyldimethylsilyloxy)-2-methylpentanal 
• 872369-15-8 (-)-(R)-4-benzyl-3-[(2R,3S)-5-(benzyloxy)-3-(tert-butyldimethylsilyloxy)-2-methylpentanoyl]-1,3-oxazolidin-2-one 
• 870091-89-7 (-)-(R)-4-benzyl-3-[(2R,3S)-5-(benzyloxy)-3-hydroxy-2-methylpentanoyl]-1,3-oxazolidin-2-one 

Downstream Products

• 1584664-46-9 C₂₅H₃₂N₂O₆*C₂HF₃O₂ 
• 1584664-41-4 (3S,4S)-4-nitrobenzyl 3-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanoyloxy)-4-methyl octanoate 
• 1584664-44-7 C₄₉H₆₆N₆O₁₂ 
• 154491-55-1 (3R,6S,9S,13S)-9-benzyl-13-[(2S)-hexan-2-yl]-6-methyl-3-(2-methylpropyl)-1-oxa-4,7,10-triazacyclotridecane-2,5,8,11-tetrone 
• 872369-31-8 (3S,4S)-3-{(R)-2-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-propionylamino]-4-methyl-pentanoyloxy}-4-methyl-octanoic acid 4-nitro-benzyl ester 
• 872369-33-0 (3S,4S)-3-{(R)-2-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propionylamino]-4-methyl-pentanoyloxy}-4-methyl-octanoic acid 
• 872369-27-2 (3S,4S)-3-((R)-2-tert-Butoxycarbonylamino-4-methyl-pentanoyloxy)-4-methyl-octanoic acid 4-nitro-benzyl ester 
• 872369-26-1 (3S,4S)-4-nitrobenzyl 3-hydroxy-4-methyl octanoate 

Relevant academic research and scientific papers

Total syntheses of arenamides A, B and C

Total syntheses of the three arenamides A-C, NFκB inhibitors, are described for the first time. The key steps involved in the synthesis are a Crimmin's aldol, Wittig olefination and a macrolactamization reaction.

Total synthesis of beauveriolide I

The first total synthesis of beauveriolide I (1a), a selective ACAT inhibitor, is described. The key steps in this synthesis involved a diastereoselective aldol condensation sequence and a macrocyclization.