870091-89-7

Upstream product

• 19790-60-4 3-Benzyloxypropanal 
• 101711-78-8 (3R)-3-propionyl-4-benzyloxazolidin-2-one 

Downstream Products

• 1245925-56-7 C₁₅H₂₀O₃ 
• 1609268-85-0 C₁₆H₂₂O₃ 
• 1609268-87-2 C₂₇H₃₅NO₆ 
• 1609268-88-3 C₂₈H₃₇NO₆ 
• 1609268-89-4 C₁₈H₃₀O₄ 
• 1609268-90-7 C₂₄H₄₄O₄Si 
• 1609268-82-7 C₁₅H₂₄O₄ 
• 1609268-84-9 C₁₈H₂₈O₅ 
• 1609268-81-6 C₂₅H₃₁NO₆ 
• 1412893-39-0 C₄₈H₇₃N₅O₉ 
• 1412893-38-9 C₄₈H₇₃N₅O₉ 

Relevant academic research and scientific papers

Total synthesis of beauveriolide I

The first total synthesis of beauveriolide I (1a), a selective ACAT inhibitor, is described. The key steps in this synthesis involved a diastereoselective aldol condensation sequence and a macrocyclization.

Studies towards the Synthesis of (-)-Pulvomycin: Construction of the C12-C40 Segment by a Stereoselective Aldol Reaction

A convergent strategy was developed for the synthesis of the C12 C40 segment of ( )-pulvomycin. Key step was a diastereoselective aldol reaction between a chiral ethyl ketone representing the C24 C40 fragment and a chiral aldehyde representing the C12 C23

Stereocontrolled synthesis of the C1-C7 fragment of enigmazole a

An enantio- and stereoselective synthesis of the C1-C7 fragment of enigmazole A is described. The three asymmetric centers of the molecule were constructed efficiently by using Evans chiral auxiliary protocol.

Total syntheses of 28,29-diepi-arenamide A, 29-epi-arenamide A, and 28-epi-arenamide A

This communication describes the synthesis of stereochemical analogs of arenamide A, a 19-membered cytotoxic depsipeptide isolated from the fermentation broth of a marine bacterial strain Salinispora arenicola. The key steps are diastereoselective aldol r

An improved synthesis of (-)-brevisamide, a marine monocyclic ether amide of dinoflagellate origin

An improved synthesis of (-)-brevisamide a marine cyclic ether isolated from the red-tide dinoflagellate Karenia brevis was achieved. The ether ring portion was constructed from an unsaturated lactone, which was prepared enantioselectively via an Evans aldol reaction and one-pot lactonization in the presence of excessive base after an Ando reaction. The ether ring and a dienol side chain fragment were connected via Suzuki-Miyaura coupling.

Asymmetric synthesis of the C1-C13 fragment of the marine metabolite bistramide K

A synthetic study on the construction of the C1-C13 fragment of bistramide K is described. This unit differs from other members of the bistramide family, which are equipped with a pyran structure at C6-C11. In bistramide K, the linear C1-C13 portion conta

A general synthetic approach for the synthesis of β-hydroxy-δ-lactones: asymmetric total synthesis of prelactones and epi-prelactones V and E

A general synthetic approach for the synthesis of prelactones and epi-prelactones V and E has been reported using an Evans' aldol reaction as the key step.

Total synthesis of (-)-ulapualide A, a novel tris-oxazole macrolide from marine nudibranchs, based on some biosynthesis speculation

A new, second generation, total synthesis of ulapualide A (1), whose stereochemistry was recently determined from X-ray analysis of its complex with the protein actin, is described. The synthesis is designed and based on some speculation of the biosynthet

Total synthesis of (-)-ulapualide A: The danger of overdependence on NMR spectroscopy in assignment of stereochemistry

Lessons learnt: The asymmetric total synthesis of the macrolide (-)-ulapualide A has been accomplished. Interestingly, the 1H NMR spectrum and chiroptical data of the macrolide and of a previously synthesized diastereoisomer with opposite stere

Studies toward the total synthesis of tedanolide: stereoselective synthesis of the C(8)-C(17) segment

The stereoselective synthesis of the C(8)-C(17) sub-unit (-)-5 of tedanolide (1), which involves iterative Evans aldol reactions as the key steps, is described.