87241-64-3Relevant academic research and scientific papers
From Carbamate to Chalcone: Consecutive Anionic Fries Rearrangement, Anionic Si → C Alkyl Rearrangement, and Claisen-Schmidt Condensation
Kumar, Singam Naveen,Bavikar, Suhas Ravindra,Pavan Kumar, Chebolu Naga Sesha Sai,Yu, Isaac Furay,Chein, Rong-Jie
, p. 5362 - 5366 (2018)
A highly efficient one-pot procedure was developed for the synthesis of various 2′-hydroxychalcones from phenyl diethylcarbamate, featuring consecutive Snieckus-Fries rearrangement, anionic Si a?' C alkyl rearrangement, and Claisen-Schmidt condensation in a single operation. The applicability of this protocol was demonstrated by the highly efficient synthesis of the anti-inflammatory natural product lonchocarpin. The mechanism insight is also provided.
SYNTHESIS OF 6- AND 8-PHENYL-SUBSTITUTED FLAVONOIDS.
Matsumura,Tsuchiya,Takeda,Imafuku
, p. 2037 - 2043 (2007/10/02)
3-Acetylbiphenyl-4-ol and -2-ol were condensed with substituted benzaldehydes to give respectively 5 prime - and 3 prime -phenyl-substituted chalcones which were cyclized to afford 6- and 8-phenylflavanones. The chalcones also gave the corresponding 6- an
