87246-92-2Relevant academic research and scientific papers
Asymmetric Cyclization of N-Sulfonyl Alkenyl Amides Catalyzed by Iridium/Chiral Diene Complexes
Nagamoto, Midori,Yanagi, Tomoyuki,Nishimura, Takahiro,Yorimitsu, Hideki
, p. 4474 - 4477 (2016/09/28)
Iridium/chiral diene complexes efficiently catalyzed the asymmetric cyclization of N-sulfonyl alkenyl amides to give the corresponding 2-pyrrolidone derivatives with high enantioselectivity. A mechanistic study revealed that the reaction proceeds via nucleophilic attack of the amide on the alkene moiety.
