872513-99-0Relevant articles and documents
Methods for the synthesis of dicarba bridges in organic compounds
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Page/Page column 116; 128; 129; 130, (2015/11/17)
The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.
An efficient protocol for the cross-metathesis of sterically demanding olefins
Wang, Zhen J.,Jackson, W. Roy,Robinson, Andrea J.
, p. 3006 - 3009 (2013/07/26)
Cross-metathesis of a wide range of previously unreactive, sterically demanding alkenes can be achieved in fair to excellent yield using a commercially available catalyst by a facile strategy involving reversal of steric preference.
Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides
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Page/Page column 62-63; 16, (2010/11/28)
According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.
Controlled synthesis of (S,S)-2,7-diaminosuberic acid: A method for regioselective construction of dicarba analogues of multicystine-containing peptides
Elaridi, Jomana,Patel, Jim,Jackson, W. Roy,Robinson, Andrea J.
, p. 7538 - 7545 (2007/10/03)
(Chemical Equation Presented) A method to facilitate regioselective formation of multiple dicarba isosteres of cystine is described. A sequence of ruthenium-catalyzed cross metathesis and rhodium-catalyzed hydrogenation of nonproteinaceous allylglycine de