548490-77-3

Usage

General Description

2,4-Pentadienoic acid, 2-(acetylamino)-, methylester, (2Z)-(9CI) is a chemical compound with the molecular formula C9H11NO2. It is also known as methylethanimidate and is classified as an ester of 2,4-pentadienoic acid. This chemical is commonly used in the synthesis of various pharmaceuticals and agrochemicals. Its use as a building block for organic synthesis is also of interest to researchers. Methylethanimidate is a colorless liquid with a strong, pungent odor, and it is known to be flammable and have detrimental effects on human health. Overall, this chemical compound is valued for its versatile applications in the fields of medicine, agriculture, and organic chemistry.

Upstream product

• 89524-99-2 methyl 2-acetylamino-2-(dimethoxyphosphinyl)acetate 
• 107-02-8 acrolein 
• 73198-56-8 N-acetyl-α-methoxyglycine methyl ester 

Downstream Products

• 872513-99-0 (2S,7S)-dimethyl 2,7-N,N-dibenzoylaminooct-4-enedioate 
• 947154-86-1 (2E,7S)-dimethyl 2-N-acetylamino-7-N-benzoyl-aminoocta-2,4-dienedioate 
• 2622-14-2 tricyclohexylphosphine 
• 38470-14-3 (2R)-pipecolinic acid hydrochloride 

Relevant academic research and scientific papers

Methods for the synthesis of dicarba bridges in organic compounds

The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.

Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides

According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.

Synthesis of the octahydroindole unit of aeruginosins via asymmetric hydrogenation of the Diels-Alder adducts of 2-amido-2,4-pentadienoate

An optically active octahydroindole, the core unit of aeruginosins (Choi) was synthesized. The Diels-Alder reaction of Danishefsky's diene with methyl (Z)-2-acetamido-2,4-pentadienoates provided the adducts regioselectively in good yield. The adducts were

One-pot tandem enantioselective hydrogenation-hydroformylation synthesis of cyclic α-amino acids

Five- and six-membered cyclic amino acids can be prepared in good yield with high ee (> 95%) via tandem rhodium-DuPHOS catalysed asymmetric hydrogenation followed by a rhodium-catalysed hydroformylation-cyclisation sequence in a single pot. The synthesis can be achieved using Rh-DuPHOS as the sole catalyst.