872607-89-1

Basic information

• Product Name: 1-Methyl-1H-indazole-5-carbaldehyde
• Synonyms: 1-Methyl-1H-indazole-5-carbaldehyde;1-methylindazole-5-carbaldehyde;1-Methyl-1H-indazole-5-carboxaldehyde;5-Formyl-1-methyl-1H-indazole
• CAS NO: 872607-89-1
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.18
• Product Categories: Building Blocks;Indazole
• Mol File: 872607-89-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 311.8°C at 760 mmHg
• Flash Point: 142.4°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 0.000549mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.47±0.30(Predicted)
• CAS DataBase Reference: 1-Methyl-1H-indazole-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-1H-indazole-5-carbaldehyde(872607-89-1)
• EPA Substance Registry System: 1-Methyl-1H-indazole-5-carbaldehyde(872607-89-1)

Safety Data

• Hazardous Substances Data: 872607-89-1(Hazardous Substances Data)

Usage

General Description

1-Methyl-1H-indazole-5-carbaldehyde is a chemical compound with the molecular formula C9H8N2O. It is a yellow liquid with a strong odor, and is primarily used as a synthetic intermediate in the production of pharmaceuticals, dyes, and other organic compounds. The compound is known for its ability to undergo various chemical reactions, including oxidation, reduction, and condensation. It is also used as a building block in the synthesis of diverse bioactive compounds, making it an important chemical in the field of organic chemistry and drug discovery. Additionally, 1-Methyl-1H-indazole-5-carbaldehyde is considered to be a potentially hazardous chemical and should be handled and stored with appropriate safety precautions.

InChI:InChI=1/C9H8N2O/c1-11-9-3-2-7(6-12)4-8(9)5-10-11/h2-6H,1H3

Upstream product

• 253801-04-6 1H-indazole-5-carbaldehyde 
• 74-88-4 methyl iodide 
• 465529-57-1 5-bromo-1-methyl-1H-indazole 
• 68-12-2 N,N-dimethyl-formamide 
• 189107-45-7 1-methyl-1H-indazole-5-carbonitrile 
• 914311-53-8 5-bromo-2-fluoro-benzaldehyde O-methyl-oxime 
• 53857-57-1 5-bromo-1H-indazole 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 

Downstream Products

• 1619884-79-5 (E)-N-(3,4-dichlorophenyl)-1-(1-methyl-1H-indazol-5-yl)methanimine 
• 1159511-24-6 1-(1-methyl-1H-indazol-5-yl)ethan-1-one 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF TUMORS

The present invention relates to compounds of Formula (Ia) or pharmaceutically acceptable salts, hydrates, solvates, clathrates, polymorphs, stereoisomers thereof. It further discloses a pharmaceutical composition comprising compounds of Formula (Ia) and the use of compounds of Formula (Ib), in particular for the use in the treatment of diseases or disorders wherein disrupting Rad51-BRCA2 interaction is beneficial.

HETEROCYCLIC OXIME COMPOUNDS

The invention relates to compounds of formula (I) and salts thereof wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).

SUBSTITUTED DIKETOPIPERAZINES AS OXYTOCIN ANTAGONISTS

Compounds of formula (I); wherein R1 is 2-indanyl, R2 is 1-ethylpropyl, R3 is a heterocyclic group optionally substituted by one or more C1-6 alkyl groups, R4 represents methyl and R5 repre