87269-98-5

Basic information

• Product Name: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester
• Synonyms: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester
• CAS NO: 87269-98-5
• Molecular Weight: 383.444
• Mol File: 87269-98-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester(CAS DataBase Reference)
• NIST Chemistry Reference: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester(87269-98-5)
• EPA Substance Registry System: (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester(87269-98-5)

Safety Data

• Hazardous Substances Data: 87269-98-5(Hazardous Substances Data)

Usage

General Description

The chemical "(1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester" is a complex organic compound with a long and specific chemical structure. It is an ethyl ester derivative of 4-oxo-4-phenylbutanoic acid, containing an additional methyl and phenyl group, as well as an amino group attached to an ether moiety. (1'S,2S)-2-(1'-Methyl-2'-oxo-2'-phenylmethoxy-ethylamino)-4-oxo-4-phenyl-buttersaeure-ethylester likely has pharmaceutical applications due to its structural similarity to known pharmacologically active compounds, and it may have potential as a drug candidate or pharmacological tool in research. However, further research and testing are needed to fully understand its properties and potential uses.

Upstream product

• 64-67-5 diethyl sulfate 
• 15121-89-8 ethyl 3-benzoyl acrylate 
• 42854-62-6 L-alanine benzyl ester p-toluenesulfonate 
• 15121-89-8 ethyl (E)-4-oxo-4-phenyl-2-butenoate 
• 17831-02-6 D-alanine benzyl ester 
• 17831-01-5 H-Ala-OBzl 

Downstream Products

• 87269-88-3 2--L-alanyl>-(1S,3S,5S)-2-azabicyclo<3.3.0>octane-3-carboxylic acid benzylester 
• 87333-19-5 Ramipril 
• 87269-99-6 N-[(1S)-1-ethoxycarbonyl-3-phenyl-3-oxopropyl]-L-alanine 
• 82717-96-2 [1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanine 

Relevant articles and documents

Preparation method of N-[1-(S)-ethoxy carbonyl-3-phenyl propyl]-L-alanine

The invention provides a preparation method of N-[1-(S)-ethoxy carbonyl-3-phenyl propyl]-L-alanine. The preparation method comprises the following steps: performing addition reaction on a compound I and a compound II under the action of a first catalyst to obtain an addition product, wherein the first catalyst is selected from a first thiourea compound and/or a urea compound; performing hydrogenation reaction on the addition product to obtain the N-[1-(S)-ethoxy carbonyl-3-phenyl propyl]-L-alanine. The first catalyst (the first thiourea compound and/or the urea compound) can be added to the reaction system, the selectivity of the addition reaction is improved and the separation efficiency of the required product in the addition reaction process is improved, so that the yield of the final product N-[1-(S)-ethoxy carbonyl-3-phenyl propyl]-L-alanine is increased. The method has the advantages of being short in synthesis route, simple in aftertreatment, capable of being applied to industrialized production and the like.

Addition of enantiomerically pure amines to activated olefines II. On the addition to ethyl (E)-4-oxo-4-phenyl-2-butenoate

The addition of (S)-phenethylamine to ethyl (E)-4-oxo-4-phenyl-2-butenoate shows no kinetic selectivity, whereas - according to the b,pl,H-rule the AB-and BB-product are kinetically preferred in the addition of (S)-alanine-isopropylester and -benzylester,