87273-77-6

Basic information

• Product Name: Acetic acid, (1-acetyl-2-pyrrolidinylidene)-, ethyl ester, (2E)-
• CAS NO: 87273-77-6
• Molecular Formula: C10H15NO3
• Molecular Weight: 197.234
• Mol File: 87273-77-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetic acid, (1-acetyl-2-pyrrolidinylidene)-, ethyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (1-acetyl-2-pyrrolidinylidene)-, ethyl ester, (2E)-(87273-77-6)
• EPA Substance Registry System: Acetic acid, (1-acetyl-2-pyrrolidinylidene)-, ethyl ester, (2E)-(87273-77-6)

Safety Data

• Hazardous Substances Data: 87273-77-6(Hazardous Substances Data)

Upstream product

• 35150-22-2 (Z)-ethyl 2-(pyrrolidin-2-ylidene)acetate 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Asymmetric synthesis of homoproline derivatives via Rh(I)-catalyzed hydrogenation using chiral bisphosphines as ligands

It has been demonstrated for the first time that Rh(I)-catalyzed asymmetric hydrogenation of cyclic β-enamino acid derivatives 1 using chiral bisphosphines could be a highly efficient synthetic method for optically active homoproline derivatives. The enantioselectivity and conversion yield were largely dependent upon the chiral ligand. Using the Me-BDPMI forming a seven-membered metal chelate, the N-acetylated β-enamino acid methyl ester 1a was hydrogenated to give optically active homoproline derivative 2a with 100% conversion and 96% ee.