87274-22-4Relevant academic research and scientific papers
Synthesis of Functionalized Aliphatic Acid Esters via the Generation of Alkyl Radicals from Silylperoxyacetals
Matsumoto, Akira,Shiozaki, Yoko,Sakurai, Shunya,Maruoka, Keiji
, p. 2431 - 2434 (2021)
We describe a catalytic method for the synthesis of a variety of functionalized aliphatic acid esters using silylperoxyacetals, which are versatile alkyl radical precursors with a terminal ester moiety. In the presence of an appropriate transition-metal catalyst, the in situ generation of alkyl radicals and the subsequent bond-forming process proceeds smoothly to afford synthetically valuable aliphatic acid derivatives. The present method can be applied to the efficient synthesis of a pharmaceutically important 1,1-diarylalkane motif. In addition, a novel strategy for the synthesis of structurally diverse hydroxy acid derivatives via a C?O bond formation process that utilizes TEMPO has been developed.
PHOTOCHEMISTRY OF α,α-DISUBSTITUTED BICYCLIC CYCLOBUTANONES - A POTENTIAL THERMAL-PHOTOCHEMICAL METATHESIS REACTION
Lee-Ruff, Edward,Hopkinson, Alan C.,Kazarians-Moghaddam, Hira
, p. 2067 - 2070 (2007/10/02)
Under certain conditions the photolysis of α,α-disubstituted cyclobutanones give terminal olefinic esters.A two-stage thermal photochemical metathesis is described.
