87281-04-7

Basic information

• Product Name: Formamide, N-(2-hydroxy-1-phenylethyl)-, (R)-
• CAS NO: 87281-04-7
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Mol File: 87281-04-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Formamide, N-(2-hydroxy-1-phenylethyl)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Formamide, N-(2-hydroxy-1-phenylethyl)-, (R)-(87281-04-7)
• EPA Substance Registry System: Formamide, N-(2-hydroxy-1-phenylethyl)-, (R)-(87281-04-7)

Safety Data

• Hazardous Substances Data: 87281-04-7(Hazardous Substances Data)

Upstream product

• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 
• 56613-80-0 D-2-phenylglycinol 
• 875-74-1 (R)-phenylglycine 
• 24461-61-8 (R)-Phenylglycine methyl ester 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 87281-06-9 (R)-O-acetyl-2-isocyano-2-phenylethanol 
• 87281-05-8 (R)-N-formyl-O-acetyl-2-amino-2-phenylethanol 

Relevant articles and documents

N-Formylsaccharin: A new formylating agent

N-Formylsaccharin, a very cheap reagent, has been revealed to be an efficient and chemoselective formylating agent of amines. Georg Thieme Verlag Stuttgart New York.

ATROPISOMERISM IN POLYMERS. SCREW-SENSE SELECTIVE POLYMERIZATION OF ISOCYANIDES BY INHIBITING THE GROWTH OF ONE ENANTIOMER OF A RACEMIC PAIR OF HELICES.

The authors describe a method for the preparation of a polymer with an excess of either left- or right-handed helices, starting from an achiral isocyanide. To this end, they added a slowly polymerizing optically active isocyanide as comonomer to a rapidly polymerizing achiral isocyanide. CD spectra and optical rotation indicate that the screw sense of the resulting polymer samples is opposite to the one preferred by the homopolymer of the optically active comonomer. A mechanism is proposed according to which the optically active comonomer is preferentially incorporated in one of the two helices formed from the achiral isocyanide, viz. the one that corresponds to its own homopolymer.