87281-04-7

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 109-94-4 formic acid ethyl ester 
• 24461-61-8 (R)-Phenylglycine methyl ester 
• 875-74-1 (R)-phenylglycine 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 

Downstream Products

• 87281-06-9 (R)-O-acetyl-2-isocyano-2-phenylethanol 
• 87281-05-8 (R)-N-formyl-O-acetyl-2-amino-2-phenylethanol 

Relevant academic research and scientific papers

N-Formylsaccharin: A new formylating agent

N-Formylsaccharin, a very cheap reagent, has been revealed to be an efficient and chemoselective formylating agent of amines. Georg Thieme Verlag Stuttgart New York.

Rational design of chiral lithium amides for asymmetric alkylation reactions - NMR spectroscopic studies of mixed lithium amide/alkyllithium complexes

Treatment of solutions of chiral lithium amides, containing internally coordinating groups, in diethyl ether (DEE) with alkyllithiums results in the formation of chiral lithium amide/alkyllithium mixed dimers. We report the use of eight different chiral l

ATROPISOMERISM IN POLYMERS. SCREW-SENSE SELECTIVE POLYMERIZATION OF ISOCYANIDES BY INHIBITING THE GROWTH OF ONE ENANTIOMER OF A RACEMIC PAIR OF HELICES.

The authors describe a method for the preparation of a polymer with an excess of either left- or right-handed helices, starting from an achiral isocyanide. To this end, they added a slowly polymerizing optically active isocyanide as comonomer to a rapidly polymerizing achiral isocyanide. CD spectra and optical rotation indicate that the screw sense of the resulting polymer samples is opposite to the one preferred by the homopolymer of the optically active comonomer. A mechanism is proposed according to which the optically active comonomer is preferentially incorporated in one of the two helices formed from the achiral isocyanide, viz. the one that corresponds to its own homopolymer.