87294-73-3Relevant academic research and scientific papers
Synthesis of perfragilin A, B and some analogues
Ferreira, Vitor F.,Park, Aeri,Schmitz, Francis J.,Valeriote, Fred A.
, p. 1349 - 1357 (2007/10/03)
Synthesis of the cytotoxic isoquinoline quinone perfragilin A, an improved synthesis of perfragilin B and preparation of some analogues of both these compounds are described. Cytotoxicity evaluation of a number of the products is reported. The regioselectivity in Diels-Alder reactions of differently substituted benzoquinones with 2-aza-1,3-bis(t-butyldimethylsilyloxy)-1,3-butadiene is described.
