872973-83-6

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 608-31-1 2,6-Dichloroaniline 

Downstream Products

• 872973-93-8 7-chloro-1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-1,6-naphthyridin-2-(1H)-one 
• 872973-91-6 1-(2,6-dichlorophenyl)-7-hydroxy-1,6-naphthyridine-2,5-(1H,6H)-dione 
• 872973-92-7 5,7-dichloro-1-(2,6-dichlorophenyl)-1,6-naphthyridin-2-(1H)-one 
• 872973-88-1 1-(2,6-dichlorophenyl)-6-(4-methoxybenzyl)-1,6-naphthyridone-2,5,7-(1H,6H,8H)-trione 

Relevant academic research and scientific papers

Efficient synthesis of a trisubstituted 1,6-naphthyridone from acetonedicarboxylate and regioselective Suzuki arylation

An efficient five-step synthesis of 1,6-naphthyridone 3b, a p38 mitogen-activated protein (MAP) kinase inhibitor intermediate, in 32% overall yield starting from acetonedicarboxylate (ADC) is described. The synthesis began with a selective monoamidation o