872980-39-7

Upstream product

• 333359-90-3 (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 431-03-8 dimethylglyoxal 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 881736-80-7 1-chloro-2-(4-methoxy-benzyl)-4-[2,3-O-(2,3-dimethoxy-buta-2,3-diyl)-6-O-(2-trimethylsilylethoxymethyl)-β-D-glucopyranos-1-yl]-benzene 

Relevant academic research and scientific papers

D-pyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture

D-pyranosyl-substituted phenyls of general formula I [image] wherein the groups R1 to R5, X, Z and R7a, R7b, R7c are defined as in claim 1, have an inhibiting effect on the sodium-dependent glucose cotransporter SGLT. The present invention also relates to pharmaceutical compositions for the treatment of metabolic disorders.

D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture

A D-Xylopyranosyl-substituted phenyl compound of general formula I wherein the groups R1 to R5, X, Z and R7a, R7b, R7c are defined as in claim 1, have an inhibiting effect on the sodium-dependent glucose cotransporter SGLT. The present invention also relates to pharmaceutical compositions for the treatment of metabolic disorders.