873003-49-7

Upstream product

• 348626-25-5 N-allyl-5-chloro-2-thiophene-carboxamide 
• 29203-58-5 4-bromo-N-hydroxybenzenecarboximidoyl chloride 
• 29203-58-5 (Z)-4-bromo-N-hydroxybenzene-1-carbonimidoyl chloride 

Downstream Products

• 959120-17-3 5-Chloro-N-[(3-{4-[(2-hydroxyethyl)amino]phenyl}-4,5-dihydroisoxazol-5-yl)methyl]thiophene-2-carboxamide 

Relevant academic research and scientific papers

SUBSTITUTED HETEROCYCLES AND USE THEREOF

The invention relates to substituted heterocycles, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular

FACTOR XA INHIBITORS

The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.