29203-58-5

Basic information

• Product Name: 4-BROMO-ALPHA-CHLOROBENZALDOXIME
• Synonyms: 4-BROMO-ALPHA-CHLOROBENZALDOXIME;Benzenecarboximidoyl chloride, 4-bromo-N-hydroxy-;4-BROMO-N-HYDROXYBENZIMIDOYL CHLORIDE;4-Bromo-N-hydroxybenzenecarboximidoyl chloride
• CAS NO: 29203-58-5
• Molecular Formula: C₇H₅BrClNO
• Molecular Weight: 234.48
• Mol File: 29203-58-5.mol
• Article Data: 73

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-BROMO-ALPHA-CHLOROBENZALDOXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-ALPHA-CHLOROBENZALDOXIME(29203-58-5)
• EPA Substance Registry System: 4-BROMO-ALPHA-CHLOROBENZALDOXIME(29203-58-5)

Safety Data

• Hazardous Substances Data: 29203-58-5(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 25062-46-8 4-bromobenzaldehyde oxime 
• 25062-46-8 4-bromobenzaldehyde Oxime 
• 178742-95-5 ethyl 3-(ethynyl)benzoate 
• 150969-58-7 ethyl 3-<(trimethylsilyl)ethynyl>benzoate 
• 24398-88-7 ethyl 3-bromobenzoate 

Downstream Products

• 31007-64-4 3,3'-bis-(4-bromo-phenyl)-4,5,4',5'-tetrahydro-[5,5']biisoxazolyl 
• 31007-65-5 3-(4-bromophenyl)-5-vinyl-4,5-isoxazoline 
• 206535-83-3 2-(4-bromophenyl)-4,5-dihydro-1H-imidazole 
• 1262847-41-5 3-[3-(4-bromophenyl)isoxazol-5-yl]benzoic acid ethyl ester 
• 1452311-23-7 (Z)-N-benzyl-4-bromo-N'-hydroxybenzimidamide 
• 65004-19-5 3-(4-bromophenyl)-5-phenyl[1,2,4]oxadiazole 
• 954230-26-3 3-(p-bromophenyl)-5-methylisoxazole-4-carboxylic acid ethyl ester 
• 1423684-08-5 C₂₇H₂₃ClN₂O₄S 
• 1423689-72-8 C₂₈H₂₅ClN₂O₄S 
• 1423700-89-3 C₂₀H₁₇NO₄S 
• 1423700-86-0 C₁₉H₁₅NO₄S 
• 1423700-84-8 C₂₅H₂₇NO₄S 
• 1423700-79-1 C₂₅H₂₇NO₅ 
• 1265630-54-3 C₂₉H₂₅ClN₂O₅ 

Relevant articles and documents

Synthesis of gem-bisphosphonates with (3-aryl-4,5-dihydroisoxazol-5-yl)methylamino moiety

Three-component reaction between N-allyl-N-methylamine, triethyl orthoformate and diethyl phosphite affords N-[bis(diethoxyphosphoryl)methyl]-N-methyl-3-arylprop-3-en-1-amine whose cycloaddition with nitrile N-oxides gives 5-{N-[bis(diethoxyphosphoryl)met

Design, synthesis, in vitro and in silico evaluation of new 3-phenyl-4,5-dihydroisoxazole-5-carboxamides active against drug-resistant mycobacterium tuberculosis

A new series of 3-phenyl-4,5-dihydroisoxazole-5-carboxamides were designed, synthesized, and evaluated for their potency against Mtb H37Rv. Designed molecules were synthesized by one-pot cycloaddition reaction in good to excellent yields. Anti-Tubercular evaluation of all synthesized derivatives identified 6k to be highly potent (MIC 1 μg/mL) against Mtb and drug-resistant strains. All potent derivatives were found to be non-toxic when tested against Vero cells. Also, in silico studies were employed to explore the binding patterns of designed compounds to target Mycobacterial membrane protein Large-3. All derivatives exhibited excellent binding patterns with the receptor. The excellent in silico Absorption, Distribution, Metabolism, and Excretion properties and druggability parameters positions these molecules as promising lead candidates for the future development of new drugs to treat drug-resistant Tuberculosis.

Electrochemical synthesis of 1,2,4-oxadiazoles from amidoximes through dehydrogenative cyclization

A convenient and efficient method for the generation of the iminoxy radical through anodic oxidation was developed for the synthesis of 3,5-disubstituted 1,2,4-oxadiazoles fromN-benzyl amidoximes. The transformation proceeds through 1.5-Hydrogen Atom Transfer (1,5-HAT) and intramolecular cyclization. The process features simple operation, mild conditions, broad substrate scope and high functional group compatibility, and provides a facile and practical way for the preparation of 1,2,4-oxadiazoles.