873215-67-9Relevant academic research and scientific papers
4-Phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives, a novel class of selective δ-opioid agonists
Trabanco, Andres A.,Pullan, Shirley,Alonso, Jose M.,Alvarez, Rosa M.,Andres, Jose I.,Boeckx, Inge,Fernandez, Javier,Gomez, Antonio,Iturrino, Laura,Janssens, Frans E.,Leenaerts, Joseph E.,De Lucas, Ana I.,Matesanz, Encarna,Meert, Theo,Steckler, Thomas
, p. 146 - 149 (2006)
A novel series of 4-phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives has been prepared and their synthesis described herein. In vitro affinities for δ-, μ-, and κ-opioid receptors, as well as the functional activity in the [35S]GTPγS assay ar
