873225-37-7

Basic information

• Product Name: Benzoyl chloride, 4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]-
• CAS NO: 873225-37-7
• Molecular Formula: C19H12ClN3OS
• Molecular Weight: 365.843
• Mol File: 873225-37-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]-(873225-37-7)
• EPA Substance Registry System: Benzoyl chloride, 4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]-(873225-37-7)

Safety Data

• Hazardous Substances Data: 873225-37-7(Hazardous Substances Data)

Upstream product

• 124959-26-8 4-(2'-benzothienyl)-2-chloropyrimidine 
• 98437-23-1 benzo[b]thiophene-2-boronic acid 
• 873225-34-4 4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)-benzoic acid methyl ester 
• 873225-30-0 4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)-benzoic acid 

Downstream Products

• 873225-46-8 IKK Inhibitor VII 

Relevant articles and documents

Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK

The design, synthesis, and the biological evaluation of 2-benzamido-pyrimidines as novel IKK inhibitors are described. By optimization of the lead compound 3, compounds 16 and 24 are identified as good inhibitors of IKK2 with IC50 values of 40 and 25 nM, respectively. Compound 16 also demonstrated significant in vivo activity in an acute model of cytokine release.