873292-74-1

Basic information

• Product Name: 1,3-Dioxane, 4-methyl-2-[4-(1-methylsilacyclobut-1-yl)phenyl]-
• CAS NO: 873292-74-1
• Molecular Formula: C15H22O2Si
• Molecular Weight: 262.424
• Mol File: 873292-74-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxane, 4-methyl-2-[4-(1-methylsilacyclobut-1-yl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane, 4-methyl-2-[4-(1-methylsilacyclobut-1-yl)phenyl]-(873292-74-1)
• EPA Substance Registry System: 1,3-Dioxane, 4-methyl-2-[4-(1-methylsilacyclobut-1-yl)phenyl]-(873292-74-1)

Safety Data

• Hazardous Substances Data: 873292-74-1(Hazardous Substances Data)

Upstream product

• 24856-58-4 1,1-dimethoxy-1-(4-bromophenyl)methane 
• 873292-73-0 4-(1-methylsilethanyl)benzaldehyde dimethyl acetal 
• 18826-95-4 1.3-butanediol 

Relevant articles and documents

New strategies for protecting group chemistry: Synthesis, reactivity, and indirect oxidative cleavage of para-siletanylbenzyl ethers

Reported herein is a new entry in the growing arsenal of arylmethyl ether protecting groups. The parasiletanylbenzyl (PSB) ether is electronically similar to the benzyl ether. Cleavage of the PSB ether is accomplished under mild conditions-involving alkaline hydrogen peroxide - that are unique among cleavage protocols for arylmethyl ethers. Furthermore, the PSB group affords the user new flexibility in the implementation of protecting group strategies that revolve around multiple arylmethyl ether protecting groups. In addition to hydrogen peroxide-based cleavage protocols, conversion of a PSB ether into a para-methoxybenzyl (PMB) ether and assembly of a PSB ether from a pre-existing para-bromobenzyl (PBB) ether are described. Finally, a new reagent for installing PSB ethers under neutral "mix and heat" conditions is reported.