873294-98-5Relevant academic research and scientific papers
Aromatic hydrazones derived from nicotinic acid hydrazide as fluorimetric pH sensing molecules: Structural analysis by computational and spectroscopic methods in solid phase and in solution
Benkovi?,Ken?el,Parlov-Vukovi?,Kontrec,Chi?,Miljani?,Gali?
, p. 259 - 267 (2018)
Structural analyses of aroylhydrazones were performed by computational and spectroscopic methods (solid state NMR, 1 and 2D NMR spectroscopy, FT-IR (ATR) spectroscopy, Raman spectroscopy, UV–Vis spectrometry and spectrofluorimetry) in solid state and in s
Tridentate ONO ligands in vanadium(III-V) complexes - synthesis, characterization and biological activity
G?uch-Lutwin, Monika,Hodorowicz, Maciej,Jurowska, Anna,Kazek, Grzegorz,Papie?, Monika,Sapa, Jacek,Szklarzewicz, Janusz
, (2020/09/11)
The synthesis, properties, including single crystal structures and biological activity of 16 new vanadium complexes with tridentate ONO Schiff base ligands L based on 5-chloro- and 5-hydroxy-salicylaldehyde and selected hydrazides are presented. Several t
Acid–Base Properties and Kinetics of Hydrolysis of Aroylhydrazones Derived from Nicotinic Acid Hydrazide
Benkovi?,Kontrec,Tomi?i?,Budimir,Gali?
, p. 1227 - 1245 (2016/08/30)
A series of aroylhydrazones were synthesized from nicotinic acid hydrazide and differently substituted benzaldehydes. The protonation constants of the 12 resulting hydrazones, as well as of the starting compounds, were determined in methanol/water 1/1 mix
Mechanistic differences between in vitro assays for hydrazone-based small molecule inhibitors of anthrax lethal factor
Hanna, M. Leslie,Tarasow, Theodore M.,Perkins, Julie
, p. 50 - 58 (2008/09/18)
A systematically generated series of hydrazones were analyzed as potential inhibitors of anthrax lethal factor. The hydrazones were screened using one UV-based and two fluorescence-based in vitro assays. The study identified several inhibitors with IC50 values in the micromolar range, and importantly, significant differences in the types of inhibition were observed with the different assays.
