873313-01-0Relevant academic research and scientific papers
(1,3-diphenyl-1h-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases
Hsu, Tsu,Chen, Chiung-Tong,Tsai, Ting-Yueh,Cheng, Jai-Hong,Wu, Su-Ying,Chang, Chung-Nien,Chien, Chia-Hui,Yeh, Kai-Chia,Huang, Yu-Wen,Huang, Chen-Lung,Huang, Chung-Yu,Wu, Ssu-Hui,Chiang, Yi-Kun,Wang, Min-Hsien,Chao, Yu-Sheng,Chen, Xin,Jiaang, Weir-Torn
experimental part, p. 1048 - 1055 (2010/10/03)
Anumber of pyrazole compounds reported in literatures elicit anti-hyperglycemic effects. By modifying the side chain of the heterocyclic skeleton, a new chemical class of DPP-IV inhibitors structurally derived from the (pyrazol-4-yl)-methylamine scaffold
4-Functionally-substituted 3-heterylpyrazoles: XV. 3-Aryl(heteryl)-1- phenyl-4-pyrazolylmethylamines and heterocumulenes obtained therefrom
Bratenko,Panimarchuk,Mel'nichenko,Vovk
, p. 238 - 242 (2007/10/03)
By reduction of 3-aryl(heteryl)-1-phenyl-4-azidomethyl-pyrazoles in the presence of Raney nickel or by hydrazinolysis of N-[3-aryl(heteryl)-1-phenyl-4- pyrazolylmethyl]phthalimides 4-pyrazolylmethylamines were obtained that in reaction with bis(trichloromethyl) carbonate afforded 3-aryl-(heteryl)-1-phenyl- 4-pyrazolylmethyl isocyanates, and with carbon disulfide furnished 3-aryl-(heteryl)-1-phenyl-4-pyrazolylmethyl isothiocyanates. 2005 Pleiades Publishing, Inc.
