87343-21-3Relevant academic research and scientific papers
Liquid crystal compound, liquid crystal composition, polymer and application
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Paragraph 0340; 0343; 0345, (2016/10/07)
The invention a liquid crystal compound, a liquid crystal composition and a polymer and application which can suppress refractive index anisotropism due to wave lengths, display low wavelength dispersion characteristics and further display inverse wavelength dispersion. The invention discloses the compound expressed by the formula (1) and the liquid crystal composition containing the compound.
Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes
Qian, Yimin,Wertheimer, Stanley J.,Ahmad, Mushtaq,Cheung, Adrian Wai-Hing,Firooznia, Fariborz,Hamilton, Matthew M.,Hayden, Stuart,Li, Shiming,Marcopulos, Nicholas,McDermott, Lee,Tan, Jenny,Yun, Weiya,Guo, Liang,Pamidimukkala, Anjula,Chen, Yingsi,Huang, Kuo-Sen,Ramsey, Gwendolyn B.,Whittard, Toni,Conde-Knape, Karin,Taub, Rebecca,Rondinone, Cristina M.,Tilley, Jefferson,Bolin, David
, p. 2433 - 2446 (2011/06/17)
Diacylglycerol acyltransferase-1 (DGAT-1) is the enzyme that catalyzes the final and committed step of triglyceride formation, namely, the acylation of diacylglycerol with acyl coenzyme A. DGAT-1 deficient mice demonstrate resistance to weight gain on hig
Synthesis of mimics to thymidine and 5-(2''-thienyl)-2'-deoxyuridine triphosphates
Wellmar,Hornfeldt,Gronowitz,Johansson
, p. 1059 - 1076 (2007/10/03)
Dicarboxylic acid 5'-monoesters of thymidine and 5-(2-thienyl)- 2''deoxyuridine have been synthesised and evaluated as triphosphate mimics. Glutaric (25, 29), adipic (26, 30), pimelic (27, 31) and trans-1,4- cyclohexane dicarboxylic acids (28, 32) were em
1,1-Alkanediol dicarboxylate linked antibacterial agents
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, (2008/06/13)
Useful antibacterial agents in which a penicillin and/or a beta-lactamase inhibitor are linked via 1,1-alkanediol dicarboxylates are of the formula STR1 where A is the residue of certain dicarboxyic acids, R3 is H or (C1 -C3), n is zero or 1 such that when n is zero R is P or B and R1 is the residue of certain esters, H or a salt thereof; and when n is 1, one of R and R1 is P and the other is B, and P is STR2 where R2 is H or certain acyl groups, and B is the residue of a beta-lactamase inhibiting carboxylic acid; a method for their use, pharmaceutical compositions thereof and intermediates useful in their production.
