873443-66-4

Basic information

• Product Name: 2,6-dichloro-4-(o-tolyl)nicotinonitrile
• Synonyms: 2,6-dichloro-4-(o-tolyl)nicotinonitrile;3-PYRIDINECARBONITRILE, 2,6-DICHLORO-4-(2-METHYLPHENYL)-
• CAS NO: 873443-66-4
• Molecular Formula: C₁₃H₈Cl₂N₂
• Molecular Weight: 263.12202
• Mol File: 873443-66-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,6-dichloro-4-(o-tolyl)nicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dichloro-4-(o-tolyl)nicotinonitrile(873443-66-4)
• EPA Substance Registry System: 2,6-dichloro-4-(o-tolyl)nicotinonitrile(873443-66-4)

Safety Data

• Hazardous Substances Data: 873443-66-4(Hazardous Substances Data)

Usage

General Description

2,6-dichloro-4-(o-tolyl)nicotinonitrile is a chemical compound with the molecular formula C14H8Cl2N2. It is a white to light tan powder that is primarily used as an intermediate for the synthesis of pharmaceuticals and agrochemicals. 2,6-dichloro-4-(o-tolyl)nicotinonitrile is often used as a building block for the creation of various heterocyclic compounds, and it is known for its potent activity against a range of biological targets. 2,6-dichloro-4-(o-tolyl)nicotinonitrile is also known for its role in the development of new drugs and agrochemicals, as its versatile structure allows for modifications that can enhance its biological activity and selectivity. It is important to handle this compound with care and use appropriate safety measures due to its potential hazards when in contact with skin, eyes, and inhalation.

Upstream product

• 873443-64-2 1',2',3',4'-tetrahydro-5'-cyano-6'-hydroxy-4'-(2-methylphenyl)-2'-oxo-1,3'-bipyridinium, zwitter ion 
• 70625-63-7 methyl 2-cyano-3-(2-methylphenyl)-2-propenoate 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 873443-68-6 2-chloro-3-cyano-4-(2-methylphenyl)-6-(4-morpholinyl)pyridine 
• 290296-68-3 2-(3,5-bis-trifluoromethyl-phenyl)-N-methyl-N-(6-morpholin-4-yl-4-o-tolyl-pyridin-3-yl)-isobutyramide 
• 342417-06-5 4-(2-methylphenyl)-6-(4-morpholinyl)-3-pyridinecarboxamide 
• 342417-01-0 4-(2-methylphenyl)-6-(4-methylpiperazinyl)-3-pyridinecarboxamide 
• 342417-02-1 [6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl]carbamic acid methyl ester 
• 290297-25-5 methyl-[6-(4-methyl-piperazin-1-yl)-4-o-tolyl-pyridin-3-yl]-amine 
• 290297-26-6 netupitant 
• 342417-07-6 [6-(morpholin-4-yl)-4-(o-tolyl)pyridin-3-yl]carbamic acid methyl ester 
• 290297-36-8 N-methyl-N-[6-(morpholin-4-yl)-4-(o-tolyl)pyridin-3-yl]amine 

Relevant articles and documents

Process for preparation of pyridine derivatives of NK-1 receptor antagonist

The present invention provides a process for preparing a pyridine compound of the formula: wherein R1, R2, R3 and a are those defined herein.