873463-97-9Relevant academic research and scientific papers
Convenient synthesis of alkyl thioacetate from alkyl halide using a polymer-supported sodium thioacetate
Zarchi, Mohammad Ali Karimi,Nejabat, Mojgan
, p. 767 - 774 (2013/02/23)
Alkyl halides are efficiently converted to their corresponding S-alkyl thioacetates under mild and nonaqueous conditions, using polymer-supported sodium thioacetate as a new polymeric reagent at room temperature in high yields and purity. The spent polymeric reagent can be removed quantitatively by filtration and pure products can be obtained by evaporation of the solvent. The spent polymeric reagent can be regenerated and reused several times without its activity changing appreciably. Iranian Chemical Society 2012.
Fluorine-substituted dihydrobicyclomycins: Synthesis and biochemical and biological properties
Park, Boon-Saeng,Widger, William,Kohn, Harold
, p. 41 - 61 (2007/10/03)
Many studies show that selective introduction of fluorine within pharmacological agents leads to improved activities. In this study, we determine the effects of aryl fluorine substitution in 5a-(benzylsulfanyl)- dihydrobicyclomycin (3) on the in vitro inh
Inhibitors of farnesyl-protein transferase
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, (2008/06/13)
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invent
