873465-86-2Relevant academic research and scientific papers
Design and synthesis of 6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid derivatives as PPARγ activators
Kumar, Rakesh,Mittal, Amit,Ramachandran, Uma
, p. 4613 - 4618 (2007)
The design and synthesis of novel series of 6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid (pyrimidone) derivatives that are high affinity ligands for peroxisome proliferators activated receptor γ have been reported as a potential substitu
Synthesis and evaluation of azaindole-α-alkyloxyphenylpropionic acid analogues as PPARα/γ agonists
Cai, Zhefeng,Feng, Jun,Guo, Yanshen,Li, Pingping,Shen, Zhufang,Chu, Fengming,Guo, Zongru
, p. 866 - 874 (2007/10/03)
A series of azaindole-α-alkyloxyphenylpropionic acid analogues was synthesized and evaluated for PPAR agonist activities. Structure-activity relationship was developed for PPARα/γ dual agonism. One of the synthesized compound 7a was identified as a potent
