873551-20-3Relevant articles and documents
Palladium-Catalyzed α,β-Dehydrogenation of Esters and Nitriles
Chen, Yifeng,Romaire, Justin P.,Newhouse, Timothy R.
supporting information, p. 5875 - 5878 (2015/05/27)
A highly practical and general palladium-catalyzed methodology for the α,β-dehydrogenation of esters and nitriles is reported. Generation of a zinc enolate or (cyanoalkyl)zinc species followed by the addition of an allyl oxidant and a palladium catalyst results in synthetically useful yields of α,β-unsaturated esters, lactones, and nitriles. Preliminary mechanistic investigations are consistent with reversible β-hydride elimination and turnover-limiting, propene-forming reductive elimination.
MICROBIOCIDAL PYRAZOLE DERIVATIVES
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Paragraph 0146, (2015/02/19)
Compounds of the formula (I) wherein the substituents are as defined in claim 1, are useful as a pesticides.
MICROBIOCIDAL PYRAZOLE DERIVATIVES
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Page/Page column 31, (2013/09/12)
Compounds of the formula (I) wherein the substituents are as defined in claim 1, are useful as a pesticides.
CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS
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Page/Page column 112, (2013/04/10)
Cycloalkylnitrile pyrazole carboxamides as JAK inhibitors useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer are provided.
BIARYL DERIVATIVES
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Page/Page column 46, (2010/11/26)
The present invention relates to a compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, whrein: R 1 is a linear or branched alkoxy group, a cycloalkoxy group, a linear or branched lower alkyl group, etc.; R 2 is halogen atom, a lower alkyl group, etc.; Q 1 is carbon atom or nitrogen atom; Q 2 is carbon atom which may be substituted with oxo group; the formula (III) : is a single bond or a double bond; A is a group selected from the group consisting of the substituent group ±; and R 5 is hydrogen atom, a lower alkyl group, cyano group, an alkoxy group or a trialkylsilyl group; having an mGluR1 inhibiting action and being useful as treatment and/or prevention of convulsion, acute pain, cerebral disturbance such as cerebral infarction or transient cerebral ischemia onset, anxiety, chemical dependency or Parkinson's disease.