873577-58-3

Upstream product

• 873577-53-8 1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-5-(4-chloro-phenyl)-pyrrolidin-2-one 
• 873577-50-5 (R)-5-(4-Chloro-phenyl)-1-((S)-2-hydroxy-1-phenyl-ethyl)-pyrrolidin-2-one 
• 873577-48-1 (3S,7aS)-7a-(4-Chloro-phenyl)-3-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one 
• 873577-51-6 (R)-5-(4-Chloro-phenyl)-1-(1-phenyl-vinyl)-pyrrolidin-2-one 
• 873577-52-7 (R)-5-(4-chlorophenyl)pyrrolidin-2-one 
• 873577-56-1 2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3-(4-chloro-phenyl)-2-aza-spiro[4.4]non-7-en-1-one 
• 67-56-1 methanol 
• 3984-34-7 4-(4-chlorophenyl)-4-oxobutanoic acid 
• 873577-54-9 3,3-diallyl-1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-5-(4-chloro-phenyl)-pyrrolidin-2-one 

Relevant academic research and scientific papers

Synthesis of spirolactams and spiropiperidines as CCR4 receptor antagonists

The synthesis of racemic and non-racemic spirocyclic lactams that display high binding affinity toward CCR4 is described. Two distinct series of spirocycles were prepared from the common intermediate 9.