87372-77-8Relevant academic research and scientific papers
Structure-Activity Relationship Study of the Inhibition of Adrenal Cortical 11β-Hydroxylase by New Metyrapone Analogues
Hays, Sheryl J.,Tobes, Michael C.,Gildersleeve, David L.,Wieland, Donald M.,Beierwaltes, William H.
, p. 15 - 19 (1984)
Metyrapone, 2-methyl-1,2-di-3-pyridil-1-propanone (1a), is a potent reversible inhibitor of the cytochrome P-450 11β-hydroxylase enzyme system (P-45011β) of the adrenal cortex.The structural features of the metyrapone molecule have been systema
