Journal of Medicinal Chemistry p. 15 - 19 (1984)
Update date:2022-08-04
Topics:
Hays, Sheryl J.
Tobes, Michael C.
Gildersleeve, David L.
Wieland, Donald M.
Beierwaltes, William H.
Metyrapone, 2-methyl-1,2-di-3-pyridil-1-propanone (1a), is a potent reversible inhibitor of the cytochrome P-450 11β-hydroxylase enzyme system (P-45011β) of the adrenal cortex.The structural features of the metyrapone molecule have been systema
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