87374-67-2Relevant academic research and scientific papers
ELECTRON DEFICIENT HETEROAROMATIC AMMONIOAMIDATES, XXIII. HETEROAROMATIC AMMONIOAMIDATES WITH BRIDGE-HEAD ammonium-NITROGEN
Fetter, J.,Lempert, K.,Moeller, J.,Nyitrai, J.,Zauer, K.
, p. 43 - 58 (2007/10/02)
Two novel type heteroaromatic ammonioamidates of the general structure 2 with bridge-head ammonium-nitrogen, and the ammonium and amidate nitrogen as well as the amidate carbon atoms incorporated into a ring, viz. the angularly condensed dihydropyridazinoquinazoliniumolates 4 and 5 have been synthesized by cyclization of the dihydropyridazinone 15 and the aminoquinazolinium derivative 17, respectively.Cyclization of the 2-(methoxycarbonylalkyl)-3-quinazolinoamides 30 and 31 to furnish the linearly anellated type 2 compounds, 7 and 8, could not be brought about.The azides 24 and 36A did not cyclize with elimination of nitrogen to furnish compounds 5 or 6 and 9, respectively; instead, they reacted as acylating agents to give the diacylhydrazines 25 and 37, respectively.In contrast to the type 38a-38c quinazolinoamidates, compound 4 proved stable to Pyrex-filtered light.
