873869-19-3 Usage
Functional Groups
The tetrazole ring is an aromatic heterocyclic ring with four nitrogen atoms and one carbon atom. The t-butyl group is an organic group consisting of three methyl groups attached to a central carbon atom, while the methylsulfonyl group consists of a sulfur atom bonded to a methane group and an oxygen atom.
Physical Properties
1H-Tetrazole, 1-(1,1-dimethylethyl)-5-(methylsulfonyl)is a crystalline solid with a melting point of 154-156°C. It is soluble in common organic solvents such as ethanol, methanol, and acetone.
Chemical Properties
1H-Tetrazole, 1-(1,1-dimethylethyl)-5-(methylsulfonyl)is a stable compound that is resistant to heat and light. It can undergo various chemical reactions, including nucleophilic substitution and electrophilic substitution, due to the presence of the tetrazole ring and the two substituents.
Industrial Applications
1H-Tetrazole, 1-(1,1-dimethylethyl)-5-(methylsulfonyl)is used as a pharmaceutical intermediate, a chemical reagent, and a precursor in the synthesis of other organic compounds. It is also used in the production of pharmaceuticals and agrochemicals.
Potential Hazards
1H-Tetrazole, 1-(1,1-dimethylethyl)-5-(methylsulfonyl)can be hazardous if not handled properly. It may cause skin irritation, respiratory problems, and eye damage if inhaled, ingested, or absorbed through the skin. It may also be harmful to the environment if released into the air or water. Proper safety precautions should be taken when handling this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 873869-19-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,3,8,6 and 9 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 873869-19:
(8*8)+(7*7)+(6*3)+(5*8)+(4*6)+(3*9)+(2*1)+(1*9)=233
233 % 10 = 3
So 873869-19-3 is a valid CAS Registry Number.
873869-19-3Relevant articles and documents
Sultones and Sultines via a Julia-Kocienski Reaction of Epoxides
Smith, Geoffrey M. T.,Burton, Paul M.,Bray, Christopher D.
, p. 15236 - 15240 (2016/01/25)
The development of the homologous Julia-Kocienski reaction has led to the discovery of two new reaction modes of epoxides with sulfones. These pathways allow rapid and direct access to a range of γ-sultones and γ-sultines.
Improved Julia-Kocienski conditions for the methylenation of aldehydes and ketones
Aissa, Christophe
, p. 360 - 363 (2007/10/03)
The scope of the methylenation of aldehydes and ketones under optimized Julia-Kocienski conditions is broadened by using 1-tert-butyl-1H-tetrazol-5- ylmethyl sulfone. Two different Barbier-type procedures are applied with NaHMDS at -78 °C or Cs2CO3 at 70 °C. The latter conditions are also adapted for the preparation of 1,2-disubstituted olefins and intramolecular olefination reactions.
