5293-42-5

Upstream product

• 6948-30-7 5-bromoveratralaldehyde 
• 27200-84-6 methyl triphenylphosphonium bromide 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 873869-19-3 1-(tert-butyl)-5-(methylsulfonyl)-1H-tetrazole 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 110582-82-6 2,3-dimethoxy-5-ethenyl benzoic acid 
• 112374-30-8 2-<4-ethenyl-2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-6-methoxyphenyl>-1,5-bis(methoxymethoxy)-4-methoxynaphthalene 
• 112374-26-2 3-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-4,5-dimethoxystyrene 
• 112374-25-1 2,3-Dimethoxy-5-vinyl-benzoyl chloride 
• 110582-84-8 2-<4'-ethyl-2'-methoxy-1'-<2-(1,4,5-trimethoxynaphthalene)>phenyl>-4,4-dimethyl-2,3-dihydro-oxazole 
• 80155-95-9 defucogilvocarcin V 
• 107189-01-5 2-(2,3-dimethoxy-5-ethylphenyl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 107189-05-9 2,3-dimethoxy-5-ethyl benzoic acid 
• 110582-83-7 2,3-Dimethoxy-5-ethylbenzoyl chloride 
• 849669-60-9 (1S,2S,4aS,8aS)-1-[(5-Ethyl-2,3-dimethoxy-phenyl)-hydroxy-methyl]-2,5,5,8a-tetramethyl-decahydro-naphthalen-2-ol 
• 849669-48-3 (1S,2R,4aS,8aS)-1-[(5-Ethyl-2,3-dimethoxy-phenyl)-hydroxy-methyl]-2,5,5,8a-tetramethyl-decahydro-naphthalen-2-ol 
• 849669-43-8 (1R,2S,4aS,8aS)-1-(5-Ethyl-2,3-dimethoxy-benzyl)-2,5,5,8a-tetramethyl-decahydro-naphthalen-2-ol 
• 849669-49-4 (1R,2R,4aS,8aS)-1-(5-ethyl-2,3-diMethoxybenzyl)-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol 
• 849669-41-6 1-bromo-2,3-dimethoxy-5-ethylbenzene 

Relevant academic research and scientific papers

Improved Julia-Kocienski conditions for the methylenation of aldehydes and ketones

The scope of the methylenation of aldehydes and ketones under optimized Julia-Kocienski conditions is broadened by using 1-tert-butyl-1H-tetrazol-5- ylmethyl sulfone. Two different Barbier-type procedures are applied with NaHMDS at -78 °C or Cs2CO3 at 70 °C. The latter conditions are also adapted for the preparation of 1,2-disubstituted olefins and intramolecular olefination reactions.

Total synthesis of the ravidomycin aglycone (defucogilvocarcin V)

The synthesis of 1-hydroxy-10,12-dimethoxy-8-vinyl-6H-benzonaphtho-pyran-6-one 7, starting from vanillin and 1,5-dihydroxynaphthalene is described.This compound is the aglycone of the antitumor antibiotic ravidomycin and is identical with the recently reported antimicrobial agent, defucogilcocarcin V.