873945-33-6

Basic information

• Product Name: 3-Piperidinol, 1-[(1R)-1-phenylethyl]-4-[4-(phenylmethoxy)phenyl]-5-[[tris(1-methylethyl) silyl]oxy]-, (3R,4R,5S)-
• CAS NO: 873945-33-6
• Molecular Formula: C35H49NO3Si
• Molecular Weight: 559.864
• Mol File: 873945-33-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Piperidinol, 1-[(1R)-1-phenylethyl]-4-[4-(phenylmethoxy)phenyl]-5-[[tris(1-methylethyl) silyl]oxy]-, (3R,4R,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Piperidinol, 1-[(1R)-1-phenylethyl]-4-[4-(phenylmethoxy)phenyl]-5-[[tris(1-methylethyl) silyl]oxy]-, (3R,4R,5S)-(873945-33-6)
• EPA Substance Registry System: 3-Piperidinol, 1-[(1R)-1-phenylethyl]-4-[4-(phenylmethoxy)phenyl]-5-[[tris(1-methylethyl) silyl]oxy]-, (3R,4R,5S)-(873945-33-6)

Safety Data

• Hazardous Substances Data: 873945-33-6(Hazardous Substances Data)

Upstream product

• 911855-75-9 (S)-4-(4-Benzyloxy-phenyl)-1-((R)-1-phenyl-ethyl)-3-triisopropylsilanyloxy-1,2,3,6-tetrahydro-pyridine 
• 873945-34-7 (S)-4-(4-benzyloxyphenyl)-1-((R)-1-phenylethyl)-3-triisopropylsilanyloxy-1,2,3,4-tetrahydropyridine 

Downstream Products

• 873945-31-4 (3R,4R,5S)-4-(4-hydroxy-phenyl)-5-triisopropylsilanyloxy-piperidin-3-ol 

Relevant articles and documents

Substituted piperidines as therapeutic compounds

Described are compounds of the general formula (I) and pharmaceutically acceptable salt thereof, in which R2, R3, W,and X have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II an

3,4,5-Substituted piperidines as therapeutic compounds

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3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS

The application relates to novel substituted piperidines of the general formula (II) in which R1, R2', R2'', R4', X, Z, m and n have the meanings defined in the description, to a process for the preparation thereof and to the use of these compounds as medicines, especially as renin inhibitors.