873975-73-6

Upstream product

• 1030-27-9 4-dimethylamino-chalcone 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 98-86-2 acetophenone 
• 862201-26-1 3-[4-(dimethylamino)phenyl]-4-nitro-1-phenylbutan-1-one 

Downstream Products

• 1021175-75-6 BF₂-chelated-[3-(4-dimethylaminophenyl)-5-phenyl-1H-pyrrol-2-yl][3-(4-dimethylaminophenyl)-5-phenylpyrrol-2-ylidene]amine 

Relevant academic research and scientific papers

Silver-coordinated aza-pyrrolidone complex, and preparation method and application thereof

The invention discloses a silver-coordinated aza-pyrrolidone complex, and a preparation method and application thereof. The complex is composed of an aza-pyrrolidone ligand, a silver metal center and a triphenylphosphine auxiliary ligand, the raw materials are relatively cheap, and the synthesis method is simple; and the prepared complex shows relatively strong absorption in an ultraviolet region and a near-infrared region, and can be excited by near-infrared light, so that the damage of an excitation light source to a biological sample can be weakened, and the complex has relatively deep tissue penetration depth in the field of living body application, and is more suitable for biological imaging and deep photodynamic photo-thermal combined treatment.

Zinc-coordinated aza-pyrrolidone optical diagnosis and treatment reagent with long-wave absorption characteristic as well as preparation and application thereof

The invention discloses a zinc-coordinated aza-pyrrolidone optical diagnosis and treatment reagent with a long-wave absorption characteristic as well as preparation and application thereof. The optical diagnosis and treatment reagent is composed of a metal center and an aza-pyrrolidone auxiliary ligand; the whole preparation process is simple, the prepared complex has a long absorption wavelength, and the absorption wavelength can be prolonged along with the change of the aza-pyrrolidone auxiliary ligand, so that the optical diagnosis and treatment reagent has a deep tissue penetration depth in the field of living body application; the complex can be excited by near-infrared light and can emit near-infrared light, so that the damage of an excitation light source to a biological sample can be weakened; and the complex can be used in the field of photodynamic and photothermal combined therapy guided by biological imaging, and has an important application prospect.

Synthesis of Aza-BODIPY boron difluoride PDT agents to promote apoptosis in HeLa cells

BF2 Chelated azadipyrromethene dyes fluoresce in the near infrared and have potential applications in photodynamic therapy. When irradiated above 600nm these aza-BODIPY compounds react with triplet O 2 in the body to form a reactive