873980-68-8

Upstream product

• 120-71-8 Cresidine 
• 6962-44-3 N-(2-methoxy-5-methylphenyl)acetamide 
• 873386-32-4 acetic acid-(4-bromo-2-methoxy-5-methyl-anilide) 

Downstream Products

• 1268153-80-5 2-amino-4-methyl-5-bromophenol 
• 1390657-47-2 N,N-dibenzyl-4-bromo-2-methoxy-5-methylbenzenamine 
• 1345118-12-8 N-[5-(2,5-dimethylbenzoxazol-6-yl)(2-pyridyl)](2-chlorophenyl)carboxamide 
• 1268037-03-1 6-bromo-5-methylbenzoxazole 
• 1345118-01-5 N-[5-(5-methylbenzoxazol-6-yl)(2-pyridyl)](2-fluorophenyl)carboxamide 
• 1578243-93-2 N-(2-methoxy-5-methyl-4-(1-methyl-1H-pyrazol-4-yl)phenyl)-8-(1-methyl-1H-pyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine 
• 1578246-10-2 2-methoxy-5-methyl-4-(1-methyl-1H-pyrazol-4-yl)aniline 

Relevant academic research and scientific papers

SMALL MOLECULE INHIBITORS OF COLONY STIMULATING FACTOR-1 RECEPTOR (CSF-1R) AND USES THEREOF

Compounds of formula (I), which are useful as CSF-1R inhibitors, are provided. Also provided are pharmaceutical compositions and kits comprising said compounds, as well as methods and uses pertaining to said compounds.

PYRAZOLYL-BASED CARBOXAMIDES USEFUL AS CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL (ICRAC) INHIBITORS

The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in pa

INHIBITOR COMPOUNDS

The present invention relates to compounds of formula (I), wherein R, R, Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1 - also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them

BICYCLIC INHIBITORS OF ALK

The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, wherein R1, X, Y, Z, A, B, G1, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.