873980-68-8

Basic information

• Product Name: 4-Bromo-2-methoxy-5-methylaniline
• Synonyms: 4-Bromo-2-methoxy-5-methylaniline;4-Bromo-2-methoxy-5-methyl-phenylamine
• CAS NO: 873980-68-8
• Molecular Formula: C₈H₁₀BrNO
• Molecular Weight: 216.0751
• Mol File: 873980-68-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-Bromo-2-methoxy-5-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-2-methoxy-5-methylaniline(873980-68-8)
• EPA Substance Registry System: 4-Bromo-2-methoxy-5-methylaniline(873980-68-8)

Safety Data

• Hazardous Substances Data: 873980-68-8(Hazardous Substances Data)

Upstream product

• 120-71-8 Cresidine 
• 6962-44-3 N-(2-methoxy-5-methylphenyl)acetamide 
• 873386-32-4 acetic acid-(4-bromo-2-methoxy-5-methyl-anilide) 

Downstream Products

• 1390657-47-2 N,N-dibenzyl-4-bromo-2-methoxy-5-methylbenzenamine 
• 1390657-48-3 tert-butyl 4-(4-(dibenzylamino)-5-methoxy-2-methylphenyl)piperazine-1-carboxylate 
• 1578246-10-2 2-methoxy-5-methyl-4-(1-methyl-1H-pyrazol-4-yl)aniline 
• 1578243-93-2 N-(2-methoxy-5-methyl-4-(1-methyl-1H-pyrazol-4-yl)phenyl)-8-(1-methyl-1H-pyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine 
• 1345118-12-8 N-[5-(2,5-dimethylbenzoxazol-6-yl)(2-pyridyl)](2-chlorophenyl)carboxamide 
• 1268037-03-1 6-bromo-5-methylbenzoxazole 
• 1345118-01-5 N-[5-(5-methylbenzoxazol-6-yl)(2-pyridyl)](2-fluorophenyl)carboxamide 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF COLONY STIMULATING FACTOR-1 RECEPTOR (CSF-1R) AND USES THEREOF

Compounds of formula (I), which are useful as CSF-1R inhibitors, are provided. Also provided are pharmaceutical compositions and kits comprising said compounds, as well as methods and uses pertaining to said compounds.

INHIBITOR COMPOUNDS

The present invention relates to compounds of formula (I), wherein R, R, Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1 - also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them