120-71-8 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 120-71-8 differently. You can refer to the following data:
1. brown to black crystalline chunks
2. p-Cresidine is a white crystalline solid.
Uses
Different sources of media describe the Uses of 120-71-8 differently. You can refer to the following data:
1. p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides. Dyes and metabolites, Environmental Testing.
2. 2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase.
3. p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides.
General Description
White to silver-gray odorless crystals.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Methoxy-5-methylaniline is sensitive to moisture and temperatures greater than 104°F. Incompatible with strong oxidizing agents .
Hazard
A possible carcinogen.
Fire Hazard
2-Methoxy-5-methylaniline is nonflammable.
Safety Profile
Confirmed carcinogen
with experimental carcinogenic and
neoplastigenic data. Moderately toxic by
ingestion. A skin and eye irritant. Mutation
data reported. When heated to
decomposition it emits toxic fumes of NOx.
See also ESTERS.
Potential Exposure
p-Cresidine is used as an intermediate in the production of various azodyes, printing inks, and pigments; including 11 dyes that are produced commercially in the United States. Human exposure to p-Cresidine occurs primarily through inhalation of
Carcinogenicity
p-Cresidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Check Digit Verification of cas no
The CAS Registry Mumber 120-71-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 120-71:
(5*1)+(4*2)+(3*0)+(2*7)+(1*1)=28
28 % 10 = 8
So 120-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO/c1-6-5-7(9)3-4-8(6)10-2/h3-5H,9H2,1-2H3
120-71-8Relevant articles and documents
Intrinsic Hydrophobicity versus Intraguest Interactions in Hydrophobically Driven Molecular Recognition in Water
Gunasekara, Roshan W.,Zhao, Yan
supporting information, p. 4159 - 4162 (2017/08/23)
Molecular recognition of water-soluble molecules is challenging but can be achieved if the receptor possesses a hydrophobic binding interface complementary to the guest. When the guest molecule contains more than one hydrophobic group, intrahost interactions between the hydrophobes could strongly influence the binding of the guest by its host. In a series of ornithine derivatives functionalized with aromatic hydrophobes, the most electron-rich compound displayed the strongest binding, despite its lowest intrinsic hydrophobicity.
Metal-Free Benzylic C?H Amination via Electrochemically Generated Benzylaminosulfonium Ions
Hayashi, Ryutaro,Shimizu, Akihiro,Song, Yetao,Ashikari, Yosuke,Nokami, Toshiki,Yoshida, Jun-Ichi
supporting information, p. 61 - 64 (2017/01/09)
Electrochemical oxidation of toluene derivatives in the presence of N-tosyldiphenylsulfilimine gave the corresponding benzylaminosulfonium ions, which were treated with tetrabutylammonium iodide under non-electrolytic conditions to give N-tosylbenzylamines. The transformation serves as a metal- and chemical-oxidant-free method for benzylic C?H amination. Because of high oxidation potential of N-tosyldiphenylsulfilimine the present method can be applied to synthesis of various benzylamines from functionalized toluene derivatives.
Electrochemical synthesis of 2-aryl-2H-benzotriazoles and their N-oxides by controlled potential cathodic electrolysis
Kim, Byeong Hyo,Lee, Doo Byung,Kim, Dae Ho,Han, Rongbi,Jun, Young Moo,Baik, Woonphil
, p. 841 - 850 (2007/10/03)
Using a divided cell, reductive cyclizations of o-nitrophenylazo dyes (1) toward 2-aryl-2H-benzotriazole-1-oxides (2) or 2-aryl-2H-benzotriazoles (3) were successfully accomplished by the controlled potential cathodic electrolysis reactions. 1 was transformed to 2 under neutral conditions while 1 was transformed to 3 under basic conditions.
